The Risks of Aspirin, Ibuprofen, Tylenol, and NSAID's

Risks of Non-Steroidal Anti-Inflammatory Drugs (NSAID’s)

After taking Ibroprofen for 6 months…
Persons have Three Times the risk of dying from stroke, heart attack, or other heart related problems (Marilynn Marchione, Associated Press, 4/19/2005)

1 aspirin per day therapy carries with it a 40% increased risk of stroke!
Taking 1 Vioxx, Celebrex, Bextra carries with it a 500 % increased risk of stroke!

1 in 10,000 people will die from taking Tylenol, even at lower doses…
Tylenol is the most common cause of liver failure in the United States

After 5 years on Ibuprofen ….
-Women are 50 % more likely to be diagnosed with breast cancer
-Women are 80 % more likely to develop breast tumors which are not
sensitive to hormones estrogen or progesterone (Rita Rubin, USA Today, 6/1/2005)

The New England Journal of Medicine stated…
The lifetime total amount tolerated before end stage renal or liver failure
(A) Tylenol = 1000 (at 1/day, for 365 days, reach this after 3 yrs)*
(B) Ibuprofen = 5000 (at 1/day, reach this in about 13 years)*
* note, multiple tablets per day cuts the above numbers in ½, 1/3, etc.
(C) The most common cause of liver failure in the U.S. is Tylenol
(D) One of the most dangerous pain medications is Vicodin = Tylenol w/Codeine … “by the time you handle the addiction you are often far along into end stage liver disease”.

A nationwide case-control study from Finland of Non-Steroidal Anti-Inflammatory Drugs (NSAID’s) - European Heart Journal, May 26, 2006

“In the largest population-based observational study thus far on the cardiovascular risk associated with NSAIDs, in users of both COX-2 Inhibitors (Vioxx, Celebrex, Bextra) and conventional NSAIDS (aspirin, ibuprofen, naproxen (aleve), clinoril, voltaren, etc.) the results showed”…

“None of the above anti-inflammatory drugs were found to have a protective effect against myocardial infarction among current users. Instead, the increased risk for myocardial infarction with NSAID users was between 35% - 50%.”

“In the users of conventional NSAIDs, the increased risk for myocardial
infarction was “elevated regardless of the length of use.” (even for 1 day’s use)

“The risk of serious upper gastrointestinal events [bleeding] is 200 – 500%
greater in users of NSAIDs compared to non-users. 16,500 Americans die each year from bleeding ulcers related to the use of non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, and naproxyn.”

A Harvard Medical School Study published in the Archives of Internal Medicine, February 2007;167:394-399, found that NSAID usage also lead to increased risk of high blood pressure in men they studied. Taking …

-Tylenol 6-7 pills/week increased the risk of hypertension by 34%
-Aspirin 6-7 pills/week increased the risk of hypertension by 26%
-Other NSAIDs 6-7 pills/week increased the risk of hypertension by 38%
-Tylenol or Aspirin 7-15 pills/week raised the risks to 52% and 32%, respectively